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Boric acid was first used as a topical antiseptic by Lister in 1873. It has subsequently been used in eye washes, mouthwashes, skin powders and ointments. Boric acid has also been as an irrigant for body cavities, including the pleural space, vagina, and rectum. The medical use of these solutions and irrigants has now been abandoned, because of toxicity and potential lethality. However, boric acid is used as a household disinfectant, and deaths due to accidental poisoning are still reported (16A).